One step synthesis of various aromatic substituted, 1-5-benzothiazepines carried by the reaction of different substituted chalcone with ortho-aminothiophenol in sonication at 40ºC using ferrous sulphate as catalyst.This reaction method is mild reaction conditionand hasvery short reaction time as compared to the other conven-tional methods. The structural assignment of the final product has been done by spectral techniques or other tech-niques.